Search on: VITAMIN K-DEPENDENT PROTEIN S 
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Descriptor English:   Protein S 
Descriptor Spanish:   proteína S 
Descriptor Portuguese:   Proteína S 
Synonyms English:   Cofactor Protein S
Protein S, Cofactor
Protein S, Vitamin K Dependent
Protein S, Vitamin K-Dependent
Vitamin K Dependent Protein S
Vitamin K-Dependent Protein S  
Tree Number:   D12.776.124.670
D12.776.395.642
D23.113.725
Definition English:   The vitamin K-dependent cofactor of activated PROTEIN C. Together with protein C, it inhibits the action of factors VIIIa and Va. A deficiency in protein S; (PROTEIN S DEFICIENCY); can lead to recurrent venous and arterial thrombosis. 
Indexing Annotation English:   a blood protein; an anticoagulant
Pharmacological Action:   Anticoagulants
 
Entry Combination - descr/qualif English:   Protein S/deficiency use Protein S Deficiency
 
History Note English:   93; was PROTEIN S, VITAMIN K-DEPENDENT (NM) 1979-92 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   30593 
Unique Identifier:   D017293 

Occurrence in VHL:
 

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